CHC Sterilizing-Grade PES Cartridge Filter

Product Introduction
Alioth Alipore? CHC double-layer polyethersulfone (PES) filters are suitable for a variety of sterile filtration of process fluids with both cartridge and disposable capsule format available. The filter has passed strict sterilization performance validation. It features a built-in pre-filtration layer to achieve high flow rate and capacity, and thereby optimize your process efficiency and cost effectiveness.

Data Download：

Depth Stacked DataSheet

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• Highly asymmetric Double-layer PES membrane.

• High flux and increased capacity.

• Validated reliable bacterial retention.

• Wide chemical compatibility (pH 1-14).

• 100% integrity tested.
• Buffers

• Final Fill

• Cell Culture Media

• Process Intermediates

• Water for pharmaceutical process

Product Specifications —Cartridge Filter

Product Specifications		5 inch	10 inch	20 inch	30 inch
	Diameter Maximum Length	69 mm 150 mm	69 mm 320 mm	69 mm 560 mm	69 mm 800 mm
Materials of Construction	Membrane	Hydrophilic polyethersulfone (PES)
	Supporting Layer	Polypropylene (PP)
	O-rings	Silicone、Ethylene propylene diene monomer（EPDM）
	Core/Cage/End caps/Housing	Polypropylene (PP)
Integrity testing	Bubble Point	≥3520 mbar（51 psi）(wetted with H₂O, 20℃, compressed air）
	Diffusion Flow	Test pressure 2760 mbar (40 psi)（20℃, compressed air）
		≤12.5 mL/min	≤25 mL/min	≤50 mL/min	≤75 mL/min
Working characteristics	Maximum Differential Pressure	Forward: 5.0 bar（72.5 psi）@ 25°C/3.0 bar（43.5 psi）@ 80°C Reverse: 2.0 bar（29.0 psi）@ 25°C
	Sterilization Resistance	In-line steam: 136℃, 30 min, 30 cycles Autoclave: 131℃, 30 min, 30 cycles
	Filtration Area	0.3 m²	0.6 m²	1.2 m²	1.8 m²
	Pore Size	0.45+0.2 μm
	Bacterial Retention	>10⁷ cfu/cm² B. diminuta ( ATCC^® 19146^TM )
	Biological Safety	All construction components meet the biological safety requirements refering to USP<88> Class VI plastic and USP<87>
	Indirect Food Additive	All component materials meet the requirements of Indirect Food Additive cited in EU 1935/2004/EC and FDA 21 CFR 177-182
	Cleanliness	Meets the requirements for a ‘non-fiber releasing’ filter defined in FDA 21 CFR 211.72 and 210.3 (b) (5) (6), and particulate matter meets the requirements of USP<788>
	Endotoxin	Endotoxin﹤0.25 EU/mL by LAL test method, which complies with the requirements of USP<85>
	TOC/Conductivity	TOC﹤0.5 mg/L, Conductivity﹤1.3 μS/cm
	Manufacturing Integrity	100% integrity test passed
	Manufacturing Environment	Manufactured in conformance with cGMP

Typical Flow Characteristics

Water Flow Rate and Pressure Drop -Alipore^® CHC 0.45+0.2μm Cartridge Filters

*T1, T3, B5, B7 represent different interface types, see order information for details.

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CHC Sterilizing-Grade PES Cartridge Filter